A Synthetic P-Nitrophenyl Esterase with Remarkable Substrate Selectivity

Abstract

A new linear polymer, poly(1,1,3,3,-tetramethyl-7-(-4 pyridinyl)-7- aza-2-oxa-1,3-disiladecane, 4, recently prepared and characterized in our laboratory, has been evaluated as a catalyst for hydrolysis of p-nitrophenyl esters. This synthetic material not only exhibits high levels of catalytic efficiency and conforms to the Michaelis-Menten model, but it also demonstrates enzyme-like specificity for esters derived from acids of moderate chain length with p-nitrophenyl tetradecanoate (C14) the optimum substrate.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1991
Accession Number
ADA237665

Entities

People

  • Martel Zeldin
  • Slawomir Rubinsztajn
  • Wilmer K. Fife

Tags

Communities of Interest

  • C4I

DTIC Thesaurus Topics

  • Alcohols
  • Carboxylic Acids
  • Catalysis
  • Catalysts
  • Chemical Reaction Properties
  • Chemical Synthesis
  • Chemistry
  • Efficiency
  • Hydrolysis
  • Materials
  • Military Research
  • Polymers
  • Pyridines
  • Substrates
  • Synthetic Materials
  • United States Government
  • Universities

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Polymer Science and Technology