Air Sampling for Chemotherapeutic Agents: a Literature Review

Abstract

Little industrial hygiene data exist for the assessment of airborne levels of antineoplastic agents in the hospital work place. Persons handling these agents cna be exposed by three potential routes: inhalation of aerosolized drug, transdermal absorption, and accidental ingestion resulting from lack of hand washing. Research has shown that by following all the procedures for handling cytotoxic drugs, the potential for exposure is minimal. All breathing zone air sampling results were below detectable limits. Various methods of air sampling had been used to measure concentration of antineoplastic drugs in drug preparation areas. None of these methods have been validated or standardized by the Occupational Safety and Health Administration (OSHA), American Conference of Governmental Industrial Hygienists (ACGIH), or the National Institute of Occupational Safety and Health (NIOSH).

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 01, 1991
Accession Number
ADA237983

Entities

People

  • Ivette Z. Hermon-cruz

Organizations

  • Armstrong Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Antineoplastic Agents
  • Chemotherapeutic Agents
  • Chemotherapy
  • Detection
  • Health
  • Health Care
  • Health Services
  • Hygiene
  • Liquid Chromatography
  • Literature Surveys
  • Medical Personnel
  • Neoplasms
  • Occupational Safety And Health
  • Pharmacies
  • Toxic Actions
  • United States

Readers

  • Aerosol Science/Aerosol Physics
  • Aviation Safety Risk Assessment.
  • Toxicology/Environmental Toxicology