Variation of TFAA in Liver Cells After an Inhalation of Halothane

Abstract

Trifluoroacetic acid (TFAA) which is the final metabolic substance of halothane, is discharged in urine. Its peak is around 10 hours after inhalation of halothane. The mechanism of this retardation of discharge may be attributed to the circulation of TFAA in intestines and the liver or to metabolism of halothane deposited on fatty tissues after inhalation of halothane. We previously discussed the possibility of the former. In the present work, we performed the experiment which examined the possibility of the latter.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1991
Accession Number
ADA238225

Entities

People

  • H. Fujii
  • K. Arai
  • M. Morio
  • M. Nakao
  • M. Shiraishi

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood Flow
  • Cell Membrane
  • Cells
  • Chromatography
  • Gas Chromatography
  • Intestines
  • Measurement
  • Metabolism
  • Retardation
  • Saline Solution
  • Schools
  • Tissues
  • Universities

Readers

  • Organic Chemistry
  • Pulsed Power and Plasma Physics.
  • Toxicology/Environmental Toxicology