Prevention of Influenza and Other Respiratory Diseases

Abstract

The antibody response of recruits to the standard trivalent influenza vaccine for the 1989 - 1990 season was excellent to all three components. In particular, the response to the B component was unusually good, when compared to previous years. In contrast, the response of the permanent part was not as strong, with 34% failing to reach protective titers against the HlNl antigen, and 10-12% unprotected against the other two components. Cell-mediated immunity to the influenza vaccine was measured by enumerating influenza-specific responder T cells in the peripheral blood. Vaccination doubled (from 40% to 83%) the number of individuals in whom these cells could be readily detected.

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Document Details

Document Type
Technical Report
Publication Date
Jun 30, 1991
Accession Number
ADA239657

Entities

People

  • Gordon Meiklejohn
  • Myron Levin
  • Theodore C. Eickhoff

Organizations

  • University of Colorado Health

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Air Force Facilities
  • Air Force Personnel
  • Antibodies
  • Antigens
  • Blood
  • Cells
  • Diseases And Disorders
  • Immunity
  • Influenza
  • Lymphocytes
  • Medical Personnel
  • Respiratory Tract Diseases
  • Students
  • Vaccines
  • Virus Diseases

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Mathematics or Statistics

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech