Effectiveness of the Revaccination of Hamadryas Baboons with Dried Live Plague Vaccine NIIS and Yersinia Pestis Fraction 1

Abstract

In order to prevent illnesses in plague endemic regions the USSR is using a live vaccine made on the basis of the EV plague microbe strain. Numerous studies have demonstrated that among the mass methods of plague vaccine immunization, the inhalation method has the greatest productivity, simplicity and is highly effective. At the same time it is known that a single injection of live vaccine, including by inhalation, does not ensure the formation of a lengthy and highly intensive immunity. It is therefore necessary to experimentally develop an effective vaccination system that would guarantee a high level of resistance for a lengthy time in those inoculated.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1991
Accession Number
ADA241777

Entities

People

  • A. A. Byvalov
  • V. A. Levedinskiy
  • V. I. Yevtigneyev
  • V. N. Paumov
  • Yu. V. Chicherin

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Blood
  • Hydroxides
  • Immune System Phenomena
  • Immunity
  • Immunization
  • Infection
  • Inoculation
  • Lepidoptera
  • Materials
  • Microorganisms
  • Pathogenic Bacteria
  • Resistance
  • Vaccination
  • Vaccines
  • Wound Infections

Readers

  • Distributed Systems and Data Platform Development
  • Immunology

Technology Areas

  • Biotechnology