Allostimulatory Analysis of a Newly-Defined and Widely-Distributed Mls Superantigen

Abstract

Mouse minor lymphocyte stimulating (Mls) determinants were first identified by the capacity of stimulator populations expressing these antigens to trigger proliferation of H-2-compatible responder T cells in a primary mixed lymphocyte reaction. These non-major histocompatibility complex (MHC) moieties stimulated both CD4(+) and CD8(+) T cells in vitro with a high precursor frequency.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1991
Accession Number
ADA241921

Entities

People

  • Fred D. Finkelman
  • H. B. Lejeune
  • James J. Mond
  • John J. Ryan

Organizations

  • Naval Medical Research Center

Tags

DTIC Thesaurus Topics

  • Antigens
  • B Lymphocytes
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cells
  • Classification
  • Genes
  • Genetics
  • Insensitive Explosives
  • Lymphatic System
  • Lymphocytes
  • Molecules
  • Recognition
  • Security
  • Thymocytes
  • Two Dimensional

Fields of Study

  • Biology
  • Medicine

Readers

  • Aviation Safety and Air Traffic Management
  • Immunology