Evaluation of New Antimalarials. Development of New Antimalarial Drugs

Abstract

During the last nine years, CDRI, Lucknow, has been working in close collaboration with WRAIR, Washington and AFRIMS, Bangkok for standardization of experimental models for screening of new blood schizontocidal, radical curative (anti-relapse) and causal prophylactic agents and the pre clinical efficacy trials of the compounds synthesized and developed by US Army antimalarial drug development programme and the CDRI. This joint biomedical collaborative research programme has led to the establishment of reliable anti-malarial screening models. The reproducibility of the following antimalarial screens at CDRI has been validated using standard drugs and it is encouraging to point out that our results with the standard drugs are in close agreement with the data obtained at AFRIMS, Bangkok and WRAIR, Washington.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1991
Accession Number
ADA242409

Entities

People

  • B. N. Dhawan

Organizations

  • Central Drug Research Institute

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Antimalarials
  • Blood
  • Cells
  • Clinical Trials
  • Diseases And Disorders
  • Hematologic Diseases
  • Infection
  • Laboratory Animals
  • Malaria
  • Methyl Cellulose
  • Quantum Cascade Lasers
  • Rhesus Monkeys
  • Standards
  • Test And Evaluation
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Academic Conference Management
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Biotechnology