Definition of Procedures for Chronic Exposure of Cancer-Prone Mice to Low-Level 2,450-MHz Radiofrequency Radiation

Abstract

Several published reports have implied that long-term, low-level exposure to radio-frequency radiation (RFR) may influence the growth and/or differentiation of mammalian cells in vivo. Specifically, the issue involves whether or not such RFR exposure can cause cells to differentiate into an invasive form (tumor induction) or can act as a promoter of tumor expression. To address this issue, the United States Air Force sponsors a project involving long-term exposure of tumor-prone mice to low-level 435-MHz RFR. An earlier onset, greater incidence, or faster growth rate of tumors in the irradiated group, as compared to sham irradiated controls, would suggest an enhanced tumor promotion potential. This investigation is essentially a parallel study to that being conducted at 435 MHz. The critical difference is the exposure frequency; this study will be conducted at 2,450 MHz, which is near the resonant frequency for mice. Knowledge gained from this study will contribute to the ongoing evaluation of safety standards for human exposure to RFR which is essential to the protection of military operational personnel and the general public.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1991
Accession Number
ADA242438

Entities

People

  • James H. Merritt
  • Melvin R. Frei

Organizations

  • Trinity University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Cancer
  • Cells
  • Electromagnetic Fields
  • Electromagnetic Radiation
  • Frequency
  • Laboratory Animals
  • Medical Personnel
  • Microwaves
  • Neoplasms
  • Radiation
  • Radio Frequency
  • Standards
  • Test And Evaluation
  • United States

Readers

  • Immunology and Pathology
  • Molecular and genetic basis of cancer.
  • Nuclear and Radiation Engineering.