Determinants of Infectivity of Pathogens in Vector Ticks

Abstract

This report describes progress on research in which the main goal is to define the physiological properties of ticks that determine the infectivity of pathogens that they transmit. We determined whether female deer ticks Ixodes dammini (Acari: Ixodidae) can be inseminated repeatedly and whether sperm from either mating take precedence in fertilizing eggs. By infesting deer with irradiated male I. dammini, the abundance of these vector ticks may effectively be reduced. The spirochetal agent of Lyme disease, Borrelia burgdorferi, disseminated from the guts of infected Ixodes dammini ticks following host attachment and appeared in slaiva before rapid engorgement commenced. This salivary route of infection appears to be the route of Lyme disease transmission in nature.

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Document Details

Document Type
Technical Report
Publication Date
Nov 15, 1990
Accession Number
ADA242706

Entities

People

  • Andrew Spielman

Organizations

  • Harvard University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Cell Membrane
  • Cells
  • Cellular Structures
  • Chemistry
  • Cytoplasm
  • Diseases And Disorders
  • Infection
  • Laboratory Animals
  • Lyme Disease
  • North America
  • Organelles
  • Salivary Glands
  • Skin Diseases
  • Tickborne Diseases
  • Ticks

Fields of Study

  • Biology

Readers

  • Aquatic Ecology
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Infectious Disease/Epidemiology