Effects of Pressure on Lipid Lateral Distribution in Membranes

Abstract

The goals of this research are: to develop a general method describing the relationship between the photophysical model and the fluorescence parameter, to use this general method to evaluate the adequacy of the Birks model in describing pyrene fluorescence, to use this general method to derive a new model which can satisfactorily describe pyrene fluorescence in membrane systems, to use the new model to determine the lateral distribution of pyrene-labeled phosphatidylcholine in membranes, to determine the lateral distribution of pyrene labeled lipids in membranes at high pressures, and to study other membrane phenomena at high pressures.

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Document Details

Document Type
Technical Report
Publication Date
Oct 10, 1991
Accession Number
ADA244722

Entities

People

  • Istvan P. Sugar
  • Parkson L. Chong

Organizations

  • Meharry Medical College

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biochemistry
  • Biological Sciences
  • Classification
  • Diffusion Coefficient
  • Fluorescence
  • High Pressure
  • Hydrostatic Pressure
  • Lipids
  • Membrane Lipids
  • Membranes
  • Military Research
  • Molecules
  • Phase Transformations
  • Pressure Distribution
  • Scientists

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Computational Modeling and Simulation
  • Molecular and Cellular Biochemistry