Inactivation of Hepatitis A Virus (HAV) by Chlorine and Iodine in Water

Abstract

The inactivation kinetics of hepatitis A virus (HAV), poliovirus 1 (Pl) and echovirus 1 (El) by free chlorine and Army iodine (globaline) were studied in phosphate buffered, halogen demand free-water (PBDFW) and in PBDFW supplemented with 5 NTU of clay tubdidity and 10 mg/l humic+fulvic acids. HAV was rapidly inactivated by free chlorine under all conditions tested (1-7 mg/L, 5 and 25 C, pH 4.5, 7.0 and 9.5), with 99.99% reductions in <8 minutes. Pl and El were inactivated more slowly than HAV but by >99.99% under most conditions tested. Iodine at 1 and 2 tablets per quart was effective at pH 9.5, with >99. 99% inactivation of all three viruses in <10 minutes. However, at pH 4.5 and 7.0 and S C, iodine inactivation of Pl and El was sometimes slow. Iodine may not inactivate HAV and other enteroviruses effectively under some field conditions. RA III, Hepatitis A Virus, Disinfection, Enterovirus, Water, Chlorine, Iodine, Kinetics.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1990
Accession Number
ADA247143

Entities

People

  • Mark D. Sobsey

Organizations

  • University of North Carolina at Chapel Hill

Tags

DTIC Thesaurus Topics

  • Analysis Of Variance
  • Bacteria
  • Biomedical Research
  • Chlorination
  • Culture Techniques
  • Data Analysis
  • Infectious Diseases
  • Microbiology
  • Microorganisms
  • Public Health
  • Regression Analysis
  • Statistical Analysis
  • Test Methods
  • Viruses
  • Water Purification
  • Water Quality
  • Water Supplies

Fields of Study

  • Biology

Readers

  • Environmental Engineering
  • Virology (or Medical Virology).