New Methodology for Fluorocarbon Synthesis
Abstract
Novel, general methods for the preparation of thermally stable perfluorinated organometallic reagents were developed. F-vinyl iodides were prepared as precursors to F-vinyl organometallics. A variety of polyfluorinated cadmium, zinc, and copper reagents were developed as synthetic reagents for the introduction of polyfluorinated alkyl, aryl, and allyl groups. SET chemistry was developed for the regiospecific addition of iodofluoroacetates and iodofluoromethylphosphonates to functionalized alkenes, and to accomplish a useful preparation of allylsulfonyldifluoroacetates and acetamides. Alkylation reactions and acylation reactions of -fluorocarboxy phosphorus ylides were developed as a useful entry to precursors which could be easily hydrolyzed to - fluoro ester and -fluoro- -keto esters.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1991
- Accession Number
- ADA247163
Entities
People
- Donald J. Burton
Organizations
- University of Iowa