New Therapeutic Modalities for Laser Retinal Injury
Abstract
Two grades (II and III) of retinal lesions were evaluated using clinical, histopathologic, and morphometric methods from 3 days up to 20 days after the laser insult. Morphometric parameters varied according to time and the energy of the laser used. Preliminary evaluation of the efficacy of high-dose, and continuous infusion of methylprednisolone was performed using a swivel- tethering system. Clinical study at 3 and 10 days after laser injury suggested a dramatic beneficial effect when the drug was given at 24 hours before injury and continued for 4 days. Preliminary histopathologic observation also suggested a protective effect of the treatment regimen. Morphometric analysis is underway. In addition, two human cases of laser injury to the retina were studied clinically as a basis for clinical application of therapeutic modalities. Laser; Retina; Injury; Treatment; Corticosteroids; Methylprednisolone; RA 3
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 29, 1991
- Accession Number
- ADA248603
Entities
People
- Mark O. Tso
- Tim T. Lam
Organizations
- University of Illinois at Chicago