Cellular Localization of Infrared Sources.
Abstract
During the past grant period we developed a special phase-contrast light microscope with an infrared spot illuminator. Using this microscope we were able to show that cultured mammalian tissue cells such as 3T3 cells appeared capable of locating distant, microscopic infrared light sources and aiming for them. The strongest responses were observed if the infrared light sources emitted light of wavelengths in the range of 800900 nm intermittently at rates of 30-60 pulses per min. In addition, we found that the irradiation of small spots of the cell body induced one or several changes of cell polarity in locomoting 3T3 cells. This kind of infrared 'vision' of single cells has never been observed before. It may have important conceptual implications for our approach to eukaryotic cells as well as practical implications for the control of wound healing and metastasis. Infrared, phototaxis, mammalian cells, tissue culture, motility, centrioles.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1992
- Accession Number
- ADA249795
Entities
People
- Guenter Albrecht-buehler
Organizations
- Northwestern University