Surface-Induced Dissociation of Multiply-Protonated Peptides.
Abstract
We report here surface-induced dissociation spectra of three multiply-charged peptides: doubly-protonated angiotensin I, doubly-protonated renin substrate, and triply-protonated mellitin. For comparison, the collision- activated dissociation spectra of renin substrate and mellitin are also presented. The spectra show that surface-induced dissociation provides structural information on multiply-charged peptides at sample concentrations compatible with electrospray ionization. For angiotensin I, renin substrate, and mellitin, surface collisions (100-165 eV) favor a limited number of fragmentation pathways, which are the same as those favored in collision activated dissociation experiments.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1992
- Accession Number
- ADA251264
Entities
People
- Ashley L. Mccormack
- Jennifer L. Jones
- Vicki H. Wysocki
Organizations
- Virginia Commonwealth University