Rapid Estimation of Post Exposure Incapacitation: 1. Definition of the Rotopad and Spasm Tests
Abstract
Non-lethal effects caused by chemical exposure can result in many casualties or the loss of military function/effectiveness in exposed troops. These effects include loss of coordination, mental derangement, blinding and respiratory distress and incapacitation. The chemical effect can be transient as with an anesthetic or can be a permanent chemical burn as caused by mustard. It follows that assessments of the military importance of potential warfare chemicals should include a measure of the incapacitation to be expected during and following chemical exposure. The assessment, in laboratory animals, of impaired motor function immediately following exposure to noxious chemical atmospheres, requires a simple, rapid test. There should be little or no manipulation of the animals so that tension, excitement and manipulative interference are minimized. The test should have a definite end or test point that is neither subjective nor requiring of interpretation to eliminate variability caused by different operators. Further, if the test can be done with naive animals the man-hours required for animal training can be avoided.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1992
- Accession Number
- ADA251570
Entities
People
- D. J. Risk
- R. W. Bide
Organizations
- Defence Research and Development Canada