Correlation of the Vocal Fold Vibratory Pattern to the Post-Operative Surgical Wound in the Porcine Model.
Abstract
Surgical injury to the human vocal folds causing changes in vibration, cannot be studied in a well-controlled fashion due to ethical considerations. Therefore, miniswine served as an animal model to study the effect on vibratory function after surgical injury to the vocal folds. Twelve miniswine were operated upon in staged procedures. Initially, the right true vocal folds of the miniswine were injured by creating progressively deeper biopsies from the epithelial cover through the vocalis muscle. The left true vocal fold served as a control. After healing, a second procedure was conducted to study the vibratory function utlizing stroboscopy and electroglottography during artificial phonation. These results were compared to the histological findings which showed that injury at the junction of the lamina propria and vocalis muscle caused significant vibratory dysfunction. Because the miniswine and human larynges are similar, the otolaryngologist can expect unsatisfactory phonation once injury occurs at this critical junction. RA 2; Lab animals; Swine.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 15, 1992
- Accession Number
- ADA251718
Entities
People
- Daniel I. Brooks
- Donald B. Blakeslee
- Ronald Banks
- Vincent D. Eusterman