Limited Toxicity and Mutagenicity Testing of Five Unicharge Propellant Compounds.
Abstract
Bis-(2,2-dinitropropyl) acetal/formal (-50/50'mixture) diphenyl amine stabilizer (BDNPA/F+/-DPA) were tested for oral toxicity. Groups of ten mice per dose level were fasted and administered the test article orally by gavage. Animals were observed for clinical signs and mortality at 1 and 4 hours after dosing and once daily for 14 days. Based upon the results from the Acute Oral Toxicity Study in Mice (14 Day), the definitive acute oral LD50 (combined sexes) for BDNPA/F+DPA was determined to be 2601.9 mg/kg with 95% confidence limits of 1814.0 to 3732.1 mg/kg. The definitive acute oral LD50 (combined sexes) for BDNPA/F-DPA was determined to be 3764.2 mg/kg with 95% confidence limits of 3081.4 to 4598.3 mg/kg. Oral Toxicity, Unicharge, Propellants, bis(2,2- dinitropropyl) acetal, bis-(2,2-dinitropropyl) formal, lab animals, RA III.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 31, 1992
- Accession Number
- ADA251786
Entities
People
- Victor T. Mallory
- Vincent B. Ciofalo