Noninvasive Ambulatory Assessment of Cardiac Function and Myocardial Ischemia in Healthy Subjects Exposed to Carbon Monoxide
Abstract
Carbon monoxide is of continuing interest to the military community. The transient nature of weapons firing, the spatial distribution of CO concentration, and differences in individual physiology will cause the CO dose to vary significantly among crewmembers. Continuous and noninvasive ambulatory monitoring of cardiopulmonary measurements in situ may provide an understanding of the effects of CO exposure among crewmembers in the field environment. This project evaluates the utility of combined impedance and electrocardiographic estimators of cardiac function during exercise in air and with exposure to CO. Treadmill exercise is included on test subjects for comparison with the existing body of data on exercise performance in asymptomatic patients and the body of data which reflects performance decrements with exercise and CO in normals. Upper body exercise is included to test the hypothesis that this form of exercise places a greater strain on the cardiovascular system than lower body exercise, both with and without CO exposure. All of the accomplished work to date has involved preparatory tasks, therefore no experimental results are reported. The midterm report does discuss the literature review, the experiment plan, and the development of a human exposure facility for executing the planned experiments. RA 3; Carbon monoxide; Exercise; ECG; Impedance cardiography
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 06, 1992
- Accession Number
- ADA252264
Entities
People
- Michael L. Mccartney
- Milan J. Hazucha
- Paul N. Kizakevich
Organizations
- RTI International