Cold Stress and Delayed Matching-to-Sample: The Effects of Tyrosine

Abstract

Military personnel can experience memory deficits while working in cold environments. The inability to recall standard operating procedures during cold exposure could jeopardize personal safety and military operations. It is possible that cold-induced memory deficits could, in part, be ameliorated through pharmacological intervention. To test this assumption, a delayed matching-to-sample task was used to assess working memory in rats exposed to 2 deg C or 22 deg C following tyrosine (50-200 pig/kg) or saline administration. overall matching accuracy was lower at 2 deg C than at 22 0 C. Tyrosine improved overall accuracy at 2 deg C relative to saline. The data support the hypothesis that tyrosine attenuates catecholamine depletion during cold exposure, reducing cold stress-induced performance deficits. Tyrosine, Delayed Matching-to-Sample, Rats, Short-term Memory.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1992
Accession Number
ADA254296

Entities

People

  • David Shurtleff
  • John R. Thomas
  • Stephen T. Ahlers

Organizations

  • Naval Medical Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accuracy
  • Amines
  • Amino Acids
  • Biomedical Research
  • Catecholamines
  • Central Nervous System
  • Classification
  • Government Procurement
  • Governments
  • Intervals
  • Laboratory Animals
  • Military Operations
  • Navy
  • Nervous System
  • Standards
  • Technical Information Centers
  • Tyrosine

Fields of Study

  • Biology
  • Psychology

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