The Influence of Antibodies to Selected Mosquito Immunogens on Mosquitoes Following Ingestion of Blood from an Immune Vertebrate Host.

Abstract

Our objective in this pilot project has been to examine the effects of mouse antibodies directed against concealed antigens on the life processes of the mosquito Aedes aegypti. We immunized mice with mosquito antigens prepared from sugar-fed and blood-fed mosquitoes as follows: heads and thoraces, abdomens, and dissected midguts. After determining the immune status, using an ELISA, of the immunized mice, we allowed samples of mosquitoes to obtain blood meals and then determined survivorship, fecundity; and egg viability! our results did not indicate a deleterious effect of antibodies from an immune mouse on mosquito survivorship, the number of eggs deposited (fecundity), or the viability of eggs deposited. Mosquitoes; Concealed antigens; Mosquito immunogens; Antibodies to mosquito antigens; RA 1.

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Document Details

Document Type
Technical Report
Publication Date
Aug 05, 1992
Accession Number
ADA254789

Entities

People

  • William S. Romoser

Organizations

  • Ohio University

Tags

DTIC Thesaurus Topics

  • Animal Structures
  • Antibodies
  • Blood
  • Cells
  • Chemistry
  • Digestive System Processes
  • Experimental Design
  • Immune Serums
  • Immunity
  • Immunization
  • Immunoglobulins
  • Medical Personnel
  • Physiology
  • Rodents
  • Salivary Glands
  • Statistical Analysis
  • Ticks

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Vector-Borne Disease and Entomology