Mechanisms of Microwave Induced Damage in Biologic Materials.

Abstract

Our experiments unambiguously confirm the teratogenic effects of low level electromagnetic fields. The data imply that only those embryos with a genetic predisposition display a teratogenic sensitivity to electromagnetic fields. They are alsodefinitive in establishing that exposure to ELF and AM modulated microwave fields cause alterations in the activity of ornithine decarboxylase in various cell lines in culture. An intriguing discovery that offers a clue to the signal-to-noise problem is the observation that EM fields applied for durations of several hours must exhibit temporal coherence for times of the order of at least 5 seconds or so if the signal transduction mechanism is to respond and bioeffects are to occur. This provides a first-level mechanism in the cell's noise discrimination process. We have shown that electromagnetic field exposure produces a transient enhancement of both the production and degradation rates of an intermediate reaction product (mRNA) in the sequential chain of biochemical reactions occurring within the cell.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1992
Accession Number
ADA255799

Entities

People

  • C. J. Montrose
  • D. Krause
  • J. J. Greene
  • J. M. Mullins
  • L. M. Penafiel
  • R. K. Mohr
  • R. M. Nardone
  • Richard J. Meister
  • T. A. Litovitz

Organizations

  • The Catholic University of America

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amplitude Modulation
  • Blood
  • Cell Line
  • Cells
  • Chemistry
  • Culture Techniques
  • Electric Fields
  • Electrical Engineering
  • Electromagnetic Fields
  • Electromagnetic Radiation
  • Embryos
  • Genetic Structures
  • Genetics
  • Magnetic Fields
  • Measurement
  • Mrna
  • Time Intervals

Readers

  • Electromagnetic Wave Scattering and Antenna Radiation Engineering
  • Molecular and Cellular Biology
  • Toxicology/Environmental Toxicology

Technology Areas

  • Biotechnology