Experimental Research Into High Barometric Oxygen Prevention of Guinea Pig Hearing Loss,
Abstract
Two groups of guinea pigs were exposed to an acoustical field of 125 dBSPL one kilohertz for three hours. One of these groups breathed high barometric oxygen at two atmospheres for three times prior to exposure and on 21 continuous days following exposure. They breathed this pure oxygen for one half hour each time. The other group was control and was not given pure oxygen. The indexes used to judge the results we induced potential hearing threshold of the hearing regions of the cerebral cortex and cochlea pathology. After exposure to sound, the average hearing loss of the high barometric oxygen group was 35 to 50 dB. That of the control group was 60 to 70 dB (P<0.01). The average total length of cochlear damage and the length of serious damage of the high barometric oxygen group were 80 microns and 34 microns while that of the control group was 267 and 210 microns respectively (P<0.01). The results indicate that high barometric oxygen acts to prevent and cure hearing loss.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 28, 1992
- Accession Number
- ADA255847
Entities
People
- Sun Fang
- Yin Jiacai
Organizations
- National Air and Space Intelligence Center