Emesis in Ferrets Following Exposure to Different Types of Radiation: A Dose-Response Study

Abstract

Ferrets were exposed to gamma rays (60Co), fission neutrons, high-energy electrons (18.5 MeV) or iron particles (56Fe, 600 MeV/amu) in order to establish the dose-response relationships for emesis following exposure to different types of radiation. The results showed that the mean effective doses (ED50s) for iron particles (35 cGy) and neutrons (40 cGy) were similar. High-energy electrons were the least effective radiation, with an ED50 of 138 cGy. Gamma rays, with an ED50 of 95 cGy, showed an intermediate effectiveness. The results suggest that the relative effectiveness of different types of radiation generally increases with an increase in linear energy transfer (LET), although LET is not completely predictive of relative behavioral effectiveness.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1992
Accession Number
ADA257408

Entities

People

  • Bernard M. Rabin
  • James A. Joseph
  • Matthew E. Wilson
  • Walter A. Hunt

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Alpha Particles
  • Charged Particles
  • Confidence Limits
  • Cosmic Rays
  • Data Analysis
  • Dose Rate
  • Dosimetry
  • Energy Transfer
  • Fission Neutrons
  • Galactic Cosmic Rays
  • Gamma Rays
  • High Energy
  • Ionization
  • Ionizing Radiation
  • Measurement
  • Radiation

Fields of Study

  • Physics

Readers

  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology

Technology Areas

  • Microelectronics