Retinal Information Processing for Minimum Laser Lesion Detection and Cumulative Damage
Abstract
Minimum ophthalmoscopically visual lesions are not . perceived very well by the injured person either from clinical experience or other forms of testing, certainly not with the detail that retinal images of the same size are seen. Previous experiments have suggested a model for retinal organization suitable for small detail detection but which will not detect retinal small lesions very well. Smaller lesions of a sub-threshold nature can cause histological damage but are not visible ophthalmoscopically, nor can they be demonstrated to cause a loss of function. A series of animal experiments has been carried out to test the electrophysiological responses of retinal ganglion cells with sufficient resolution to detect threshold laser exposures with possible deficits in perceiving moving spot/edges and other optical discontinuities. The results are accurate with high resolution and the results should be correlated with supra-threshold exposures of a level to cause sub- retinal hemorrhages and/or vitreous hemorrhages. Both qualitative and quantitative comparisons are needed between the kind of damage caused by sub- threshold, barely threshold, and markedly supra-threshold lesions on this aspect of retinal organization.... RA 3; Lasers; Subretinal hemorrhage; Vitrectomy; Vitreous hemorrhage.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 17, 1992
- Accession Number
- ADA259195
Entities
People
- Myron L. Wolbarsht
Organizations
- Duke University