Preclinical Toxicology Studies For New Drugs and Vaccines.

Abstract

The purpose of this study is to determine specific target organ toxicity, dose-response relationships, and a no adverse effect level of WR6026 in Beagle dogs following thirteen weeks of daily oral administration. In addition, the reversibility of these toxic effects over a 90-day recovery period will be assessed. Treatment was initiated on 5/7/92. Necropsies were conducted on 8/6-7/92 and 11/5-6/92 after the three month treatment period and a three month recovery period, respectively.

Document Details

Document Type
Technical Report
Publication Date
Dec 07, 1992
Accession Number
ADA259275

Entities

People

  • Barry S. Levine

Organizations

  • University of Illinois at Chicago

Tags

DTIC Thesaurus Topics

  • Recovery
  • Toxicity
  • Toxicology

Fields of Study

  • Medicine

Readers

  • Toxicology/Environmental Toxicology

Technology Areas

  • Biotechnology