The Assessment of the Technical Requirements of a Closed Blood Handling System Using a Tri-Enzymes for a HIV Assay. Phase 1
Abstract
This funded Research Effort assessed the technical requirements to develop a closed blood handling device and testing vehicle for Human Immunodeficiency Virus (HIV) utilizing ELISA protocol as well as the encapsulation of the multi-enzymes within the closed system. It was a design/modeling program to modify an existing single cavity cuvette developed for Non A, Non B Hepatitis to the multi/ process system required by the ELISA protocol. The Auto-cuvette prototype designed within this Research Project is a seven stage automated blood testing vehicle using Wafer Technology to encapsulate the multi-enzymes required by the ELISA protocal. The design allows complete safety from HIV contamination; (1) The coated cuvet cell is received from the supplier with a sealing foil in place for operator protection. This foil will be pierced at the first stage, (2) All offal from both wash stations is carried into a disposable reservoir, and (3) The coated cuvet cell used for absorbance measurement is automatically sealed before removal from the Auto-cuvette.... SBIR; RA I; Mathematical Modeling; Blood Testing; HIV; Elisa.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 18, 1990
- Accession Number
- ADA259395
Entities
People
- Albert E. Katzer