Study of Nephropathia Epidemica (NE) in Sweden.

Abstract

A total of 3524 rodents collected in a HFRS endemic area of Sweden were tested for Puumala (PUU) virus infection (both viral antigen in lungs and specific antibodies in serum) by ELISA. The material included 2493 Clethrionomys glareolus, 620 C. rufocanus, 367 Microtus agrestis, 39 Myopus Schisticolor and 5 Apodemus flavicollis. C. glareolus was found to be the most important vector of PUU virus. Infection rate did correlate with population density over time but with a time lag of one year. In addition monoclonal antibodies to PUU virus were generated and used for characterisation of virus and development of new diagnostic techniques. Two epidemiological studies, one in Bashkirtostan (Russia) and one among military personnel in Sweden were also performed. Sequele post HFRS in man were investigated.... Epidemiology, Immunology, BD, Foreign, RAD I.

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Document Details

Document Type
Technical Report
Publication Date
Jan 28, 1993
Accession Number
ADA261711

Entities

People

  • Bo Niklasson

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Antigens
  • Biomedical And Dental Materials
  • Blood
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Immune Serums
  • Immunoglobulins
  • Infection
  • Materials
  • Medical Personnel
  • Military Personnel
  • Pain
  • Polymeric Films
  • Ussr
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Academic Conference Management
  • Virology (or Medical Virology).