Lead Exposures and Biological Responses in Military Weapons Systems: Aerosol Characteristics and Acute Lead Effects among U.S. Army Artilleryman - Final Report

Abstract

This study was to determine the concentration and chemical nature of lead (Pb) aerosols produced during the firing of artillery and to determine the exposures and biological responses of crew members exposed to lead aerosols during such firing. The concentrations of lead-containing aerosols at crew positions depended on wind conditions, with higher concentrations when firing into a head wind. Aerosol concentrations were highest in the muzzle blast zone. Concentrations of lead in the blood of crew members rose during the first 12 days of exposure to elevated airborne lead concentrations and then leveled off. There was no rapid decrease in blood lead concentrations after completion of firing. Small decreases in hematocrit and small increases in free erythrocyte porphyrin were correlated with increasing exposure to airborne lead. These changes were reversed by seven weeks after firing. Changes in nerve conduction velocity had borderline statistical significance to airborne lead exposure. In measuring nerve conduction velocity, differences in skin temperature must be taken into account.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1993
Accession Number
ADA263938

Entities

People

  • D. P. Peterson
  • J. H. Stebbings
  • M. H. Bhattacharyya
  • Ravinder Kumar
  • Scott A. Johnson

Organizations

  • Argonne National Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Artillery
  • Biomedical Research
  • Chemical Synthesis
  • Chemistry
  • Firing Rate
  • Howitzers
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Measurement
  • Medical Personnel
  • Nervous System
  • Peripheral Nervous System
  • Regression Analysis
  • Spectra
  • Test And Evaluation
  • Urban Areas

Fields of Study

  • Environmental science

Readers

  • Materials Science and Engineering.
  • Toxicology/Environmental Toxicology
  • ballistics.