Diagnostic Challenges: Lymphotropic Sero-Questionables

Abstract

During a sero-survey for lymphotropic retroviruses, seven screening tests were performed for the three lymphotropic retroviruses of relevance in Djibouti, East Africa (HIV-1, HIV-2 and HTLV-1). Of the 82 subjects whose sera reacted in at least one retroviral screening assay, about one third could be followed, and their sera were re-examined after a 5-month interval, and then after an additional 3-month interval. Six selected individuals are reported here, whose retroviral serologies presented important and often unexplained changes over an eight-month period. The six cases summarized prototypic situations and present serological results in a style appropriate to stimulate thought on the significance and interpretation of lymphotropic viral serologies. Each case study is followed by a set of questions that formulate pertinent serological concepts.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1992
Accession Number
ADA263992

Entities

People

  • E. A. Abbatte
  • Erin E. Fox
  • G. Rodier
  • N. T. Constantine

Organizations

  • Naval Medical Research Unit Three

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Africa
  • Agglutination
  • Antibodies
  • Biomedical Research
  • Blood
  • Case Studies
  • Coinfection
  • East Africa
  • Hiv Infections
  • Infection
  • Intervals
  • Medical Personnel
  • Pcr Testing
  • Polymerase Chain Reaction
  • Proteins
  • Viruses
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Systems Analysis and Design