Preliminary Assessment of the Oral Toxicity of 1-5-Diazido-3-Nitrazapentane, 2- and 6-Week Feeding Study, Male and Female Rats

Abstract

A 2 and 6 week gavage feeding of DANPE caused testicular hypospermatogenesis in male rats and pneumonitis in female rats. A NOAEL was not achieved in male rats but was achieved in female rats at the 56.00 mg/kg/day dose level.... 1,5-Diazido-3-Nitrazapentane (DANPE), Gavage, Testicular hypospermatogenesis, Insterstitual Inflammation No-observed-Adverse-Effect- Level(NOAEL), Feeding study.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1993
Accession Number
ADA264281

Entities

People

  • Everett A. Haight
  • John G. Harvey
  • Patricia A. Bell

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Biological Laboratories
  • Blood
  • Blood Cells
  • Body Weight
  • Cells
  • Chemistry
  • Classification
  • Health
  • Hematology
  • Leukocytes
  • Lymphatic System
  • Medical Personnel
  • Rodents
  • Security
  • Toxicity

Readers

  • Toxicology/Environmental Toxicology