The Effect of Alkyl Substituents on the Macrocycle Ring on Enantiomeric Recognition by Chiral Pyridino-18-Crown-6 for 1-Naphthylethylamine
Abstract
This paper discusses the effect that various dialkyl substitutents on chiral pyridino-18-crown-6 ligands have on the molecular recognition of these ligands for the (R) and (S)-(alpha-(1-naphthyl)ethyl) ammonium perchlorate. We have systematically synthesized the necessary chiral pyridino-18-crown-6 macrocycles and determined the extent of molecular recognition by titration calorimetry. This paper also discusses possible mechanisms of recognition.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 20, 1993
- Accession Number
- ADA265513
Entities
People
- J. K. Hathaway
- J. S. Bradshaw
- L. Y. Zhu
- P. Huszthy
- Reed Izatt
Organizations
- Brigham Young University