Amperometric Biosensors Based on 3-Dimensional Hydrogel-Forming Epoxy Networks

Abstract

Proteins and glycoproteins of enzymes behave with respect to electron transport, but not ion transport, as good electrical insulators. We have shown that these insulators can be made sufficiently electron conducting to allow the flow of a current between reaction centers of redox enzymes and electrodes equaling or exceeding the current associated with the turnover of the enzymes. In order for such a current to flow it is necessary to introduce into the enzyme proteins of glycoproteins fast electron relaying centers, so as to reduce the electron transfer distances.

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Document Details

Document Type
Technical Report
Publication Date
May 24, 1993
Accession Number
ADA265528

Entities

People

  • Adam Heller
  • Dan Li Wang
  • Ruben Maidan

Organizations

  • University of Texas at Austin

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biosensors
  • Chemical Engineering
  • Chemical Synthesis
  • Chemistry
  • Detectors
  • Electron Transfer
  • Engineering
  • Hydrogels
  • Macromolecules
  • Materials Laboratories
  • Materials Science
  • Molecules
  • Organic Chemistry
  • Polymeric Films
  • Polymers
  • Three Dimensional
  • Universities

Fields of Study

  • Physics

Readers

  • Electrochemical Surface Science
  • Plasma Physics / Magnetohydrodynamics

Technology Areas

  • Biotechnology
  • Microelectronics