Final Report for Contract N00014-91-J-1815 (University of California, Santa Cruz)
Abstract
The goal of this grant was to isolate and characterize the antifouling substances from seaweeds provided by the group at Hopkins Marine Station, Pacific Grove, Calif. Overall, the objectives were accomplished. Zosteric acid was isolated and identified as the key active principle of the alga. A synthesis was developed and the group at Hopkins were trained to carry- out this synthesis work. One staff researcher, visiting professor James Todd was supported by this grant. Two manuscripts were produced from Dr. Todd's experimental work. Additional details about these publications is as follows: (1) The isolation of a monomeric carboxylic acid of swinholide A from the Indo- Pacific sponge, Theonella swinhoei , James S. Todd, K.A. Alvi, and Phillip Crews, Tetrahedron Letters, Vol. 33, No. 4, pp. 441-442,1992. (2) The antifouling activity of natural and synthesis phenolic acid sulfate esters. James S. Todd, Richard C. Zimmerman, Philip Crews, and Randall S. Alberte, Phytochemistry, in press (1993)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 10, 1993
- Accession Number
- ADA265625
Entities
Organizations
- University of California, Santa Cruz