A Mathematical Model for the Study of Hemorrhagic Shock and Fluid Resuscitation: The Systemic and Pulmonary Vasculature
Abstract
In systemic and pulmonary circuit models, the number and configuration of vascular compartments may affect predictions of vascular volume and blood flow. In this paper, we consider various models of the pulmonary and systemic vascular circuits to identify models appropriate for studies of hemorrhage and fluid resuscitation. We found that at least one pulmonary vascular compartment, made up of one resistance and one capacitance element, was required to describe the response of pulmonary blood volume to changes in pulmonary inflow rate (i.e., right heart output). Incorporation of additional pulmonary vascular segments did not alter predictions of pulmonary volume or flow rate. Therefore, one lumped pulmonary vascular compartment appears to be sufficient. It may be necessary to incorporate multiple pulmonary vascular segments, however, for studies of pulmonary transcapillary exchange or cardiovascular control.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1993
- Accession Number
- ADA266292
Entities
People
- Tammy J. Doherty
Organizations
- Letterman Army Hospital