Wound Healing after Laser Injury to Skin - The Effect of Occlusion and Vitamin E

Abstract

The skin of the Yorkshire pig was irradiated with various doses of argon and copper vapor laser and evaluated for effects on healing time of pretreatment with topical or intramuscular vitamin E or the Op-Site wound dressing Incident irradiance for both lasers was between 3.5 and 4.5 watts/CM2 for a 10-14 mm beam diameter with a near uniform intensity profile. Minimal erythemic dose for the copper vapor laser was 35 + 2 J/cm 2 (10 second exposure and 22.4 + 0.1 J/cm2(6 second exposure) for the argon laser. Three dose levels were administered: a low dose causing light erythema, an intermediate dose. and a high dose causing dermal stasis.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1993
Accession Number
ADA266473

Entities

People

  • Bruce E. Stuck
  • Gad A. Simon
  • Peter J. Schmid
  • Theordore Van Ravenswaay
  • William G. Reifenrath

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anesthesia
  • Argon Lasers
  • Bandages
  • Blood
  • Cells
  • Connective Tissue
  • Copper Vapor Lasers
  • Electromagnetic Radiation
  • Epidermis
  • Hair
  • Laboratory Animals
  • Laser Damage
  • Laser Safety
  • Lasers
  • Medical Personnel
  • Microvessels
  • Subcutaneous Tissue

Fields of Study

  • Medicine
  • Physics

Readers

  • Pulsed Power and Plasma Physics.
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Directed Energy
  • Directed Energy - Lasers