Plasmodium vivax VK247 and VK210 Circumsporozoite Proteins in Anopheles Mosquitoes from Andoas, Peru

Abstract

Anopheles mosquitoes captured in Andoas, Peru, a Plasmodium vivax- endemic area in the Peruvian Amazon region, contained both VK210 and VK247 P. vivax circumsporozoite (CS) proteins. Approximately 0.9% of the 4,403 mosquitoes tested by enzyme-linked immunosorbent assay were positive; 28% and 72% of the positive mosquitoes contained VK210 and VK247 CS proteins, respectively. These findings correlate strongly with a recent report of the presence of antibodies in residents of this area that recognize the VK210 and VK247 repeats, clearly indicating that both P. vivax CS protein polymorphs are common in the region.... Anopheles, Plasmodium spp., Circumsporozoite.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1993
Accession Number
ADA266510

Entities

People

  • Eileen D. Franke
  • Faustino Carbajal
  • James T. Need
  • Robert A. Wirtz
  • Roberto Fernandez

Organizations

  • Naval Medical Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Antibodies
  • Biological Sciences
  • Biomedical Research
  • Buildings And Structures
  • Continents
  • Detection
  • Diseases And Disorders
  • Geographic Regions
  • Identification
  • Infection
  • Malaria
  • Proteins
  • Research Facilities
  • Salivary Glands
  • South America
  • Sporozoites

Fields of Study

  • Biology
  • Medicine

Readers

  • International Relations, focusing on Korea-Africa and North Korea-South Korea relations, and Nigeria-Latin American Relations.
  • Molecular Genetics
  • Parasitology and Pharmacology of Malaria.