Efficacy of Allogenic Cultured Keratinocyte Grafts for Burn Wounds
Abstract
Our initial proposal reviewed the previous work on cultured keratinocyte grafts, specifically allografts, done over the last 15 years. The principal hypothesis of this proposal was that although keratinocytes do not express Class II histocompatibility antigens in vitro, once animals are grafted with allogeneic cultured keratinocytes these keratinocytes will sensitize the animals and lead to subsequent rejection. If this hypothesis is not true, however, keratinocyte grafts could be used as a major source of wound coverage for patients with large burns or other open wounds. This Midterm Report will review the progress on this grant as it relates to the initial proposal.... RAII, Lab Animals, Mice, Burns, Allografts, Transplants, Immunohistology.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1993
- Accession Number
- ADA267262
Entities
People
- Anthony A. Meyer
Organizations
- University of North Carolina at Chapel Hill