Effects of Endotoxin Induced Lung Injury and Exercise in Goats/Sheep

Abstract

This study was designed the effects of exercise performed on animals already injured with E. coli endotoxin. This would tell us whether exercise makes the lung injury worse. It would also tell us how much exercise performance is impaired. These studies were designed to give further insights into the underlying causes of acute lung injury. Premature termination of the study prevented completion of the research project. It appeared from the limited experimentation conducted that maximal exercise was impaired by endotoxin- induced lung injury. Conclusions regarding exacerbation of endotoxin-induced lung injury cannot be made.

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Document Details

Document Type
Technical Report
Publication Date
Jun 02, 1993
Accession Number
ADA268153

Entities

People

  • Thomas G. Mundie

Organizations

  • Tripler Army Medical Center

Tags

DTIC Thesaurus Topics

  • Arteries
  • Biological Factors
  • Biological Toxins
  • Blood
  • Blood Cells
  • Blood Gases
  • Cardiovascular System
  • Cell Count
  • Endotoxins
  • Granulocytes
  • High Explosive Ammunition
  • High Explosives
  • Laboratory Animals
  • Leukocytes
  • Lung Diseases
  • Pulmonary Hypertension
  • Wounds And Injuries

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology
  • Systems Analysis and Design