Effect of Radio-Frequency Radiation (RFR) and Diazoluminomelanin (DALM) on the Growth Potential of Bacilli
Abstract
DALM, which is thought to generate increased levels of free radicals in response to RFR, was synthesized in situ by Bacillus anthracis. Bacilli grown under DALM-producing conditions showed significantly lower plate counts in response to circularly polarized 2450 MHz RFR (100W/Kg) with exposures as short as 30 min. Bacilli grown on media for 3 days prior to irradiation demonstrated lower colony counts than 1 day old cultures under DALM-producing and nonproducing conditions. No significant RFR effects were observed for endospore preparations of bacilli grown in the absence of DALM substrates. Thus, DALM appears to function as a microwave-sensitive antibiotic which may operate through a free radical-mediated mechanism. Additionally, DALM-laden bacteria have demonstrated temperature-dependent 'slow fluorescence,' supporting the hypothesis that DALM toxicity is mediated by free radicals and suggesting that DALM may be of utility in the area of molecular electronics. Radiofrequency Radiation Effects, Bacterial Viability, Slow Fluorescence, Molecular Electronics
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1993
- Accession Number
- ADA269376
Entities
People
- John G Bruno
- Jonathan L. Kiel
Organizations
- Armstrong Laboratory