Molecular Studies of HTLV-1 Infection in Newly Recognized High Risk Population
Abstract
The report summarizes the two years of contract of the research aimed to define newly recognized high risk population for HTLV-I infection. To define the extent of HTLV-I infection among groups of Jewish immigrants to Israel with an increased frequency of Adult T-cell Leukemia (ATL). Various serological and molecular screening of methods were used, including ELISA and PCR use for molecular survey by amplification of HTLV-I proviral DNA from peripheral blood mononuclear cells DNA. overall rate of infection is 12% for Jews arriving from Khurusan-North-Eastern Iran. No positive HTLV-I carries were found from other parts of Iran, Ethiopia, and other Mid-Eastern countries, We could not identify HTLV-I seropositive patients in Insulin Dependent DiabeteS Mellitus (IDDM) patients in children with non-Burkitt lymphomas, Psoriasis and Parapsoriasis patients, DNA Sequence data for HTLV-I isolates are provided showing similar sequence to African isolates. HTLV-I, Epidemiology, Polymerase, Virus, Aids, Biotechnology, RAD I.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 10, 1993
- Accession Number
- ADA269725
Entities
People
- Yehuda Danon
Organizations
- Tel Aviv University