Plasmodium Coatneyi Ring-Infected Erythrocyte Surface Antigens
Abstract
Plasmodium coatneyi produced ring-infected erythrocyte surface antigen (RESA) during infection of the rhesus monkey. This antigen was immunogenic and elicited an antibody response that was not persistent but was boosted by repeated infections in a manner similar to that seen in P. falciparum infections in humans. Preliminary data showed that the appearance and increasing titer of antibodies to P. coatneyi RESA-like antigen were associated with prolongation of intervals from innoculation to potency and with control of parasitemia.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1993
- Accession Number
- ADA270015
Entities
People
- Arthur E. Brown
- C. S. Smith
- H. K. Webster
- Rachanee Udomsangpetch
Organizations
- Walter Reed Army Institute of Research