Structural and Biophysical Characterisation of A Glutamate Receptor
Abstract
The immediate objectives of this work, namely to isolate, purify, structurally characterise and clone insect muscle GLuR were not realised, mainly because of unforseen technical difficulties, some of which have yet to be overcome. However, unexpectedly rapid developments in the molecular for this class of receptor. We have taken advantage of these developments by designing new molecular biological procedures for over-expressing cloned mammalian GluR subunits. Since the long-term aim of this project is to produce biosensors based upon GluR, the availability of pure mammalian GluR is clearly advantageous in this respect.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1993
- Accession Number
- ADA270048
Entities
People
- E. A. Barnard
- P. N. Usherwood
Organizations
- University of Nottingham