Comparison of Single and Double Stranded DNA Binding to Polypyrrole
Abstract
The polycation conducting polymer, oxidized polypyrrole, possesses the ability to form complexes with DNA. Our previously proposed diffusion limited binding model for double helical DNA was also found to be applicable to single stranded DNA in this study. However, single stranded DNA was found to bind PPy at a higher level than double helical DNA. An investigation of electropolymerized PPy film morphology using SEM and TEM techniques revealed two distinctly differing surface morphologies for the Platinum (Pt) electrode face (smooth) and polymeric growth face (rough). The DNA uptake levels were found to be consistently different on either surface. Double stranded DNA penetration into the surface increased with extended time periods of exposure while a similar phenomenon, but to a lower extent, was observed for single stranded DNA. DNA, Polypyrrole, Conducting polymers.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1993
- Accession Number
- ADA271307
Entities
People
- D. L. Kaplan
- J. O. Lim
- K. A. Marx
- R. Pande
- Sukant K. Tripathy
Organizations
- University of Massachusetts Lowell