Serologic Evidence of Previous Campylobacter jejuni Infection in Patients with the Guillain-Barre Syndrome
Abstract
The Guillian-Barre syndrome, sometime called 'acute inflammatory polyneuropathy,' is an inflammatory demyelinating disease of peripheral nerves characterized by various degrees of weakness sensory abnormalities, and autonomic dysfunction (1-2). Since the marked decline in poliomyelitis, the Guillain-Barre syndrome has become the most common cause of acute neutomuscular paralysis in adults and children in the United States and has an annual incidence of 1.7 per 100,000 people (3,4). Epidemiologic studies in all parts of the world have confirmed the association between the Guillain-Barre syndrome and previous acute infection, especially of the respiratory or gastrointenstinal tracts (4-8). Most report that between 50% and 75% of patients have an infectious illness 1 to 3 weeks before onset of neurologic symptoms; previous diarrhea illness occurs in 10% to 30%.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 15, 1993
- Accession Number
- ADA271881
Entities
People
- Amjad A. Ilyas
- Ban Mishu
- Carol L. Koski
- Francine Vriesendorp
- Stuart D. Cook
Organizations
- Veterans Administration Medical Center