Cortical Mechanisms of Attention, Discrimination, and Motor Response to Somesthetic Stimuli
Abstract
Work carried out on AFOSR 90-0266 made major progress in several areas, including: (1) Development of technology for recording large numbers of single neurons (up to 64) simultaneously through microwires implanted at multiple levels of the somatosensory system in awake rats. (2) Utilization of an operant conditioning paradigm for investigating the detection and processing of sensory cues which trigger an active motor response. (3) Demonstration that neuronal responses in the SI and MI cortices to such sensory cues are increased when they are used to trigger a conditioned motor response. (4) Demonstration that this conditioning increases the prevalence of functional connections between neurons in the SI and MI cortices. (5) Used quantitative techniques to defined dynamic and distributed properties of receptive fields in the somatosensory cortex and thalamus. (6) Developed the use of multivariate statistical techniques to define population coding within ensembles of recorded neurons. (7) Continued to define neuroanatomical substrates for processing within this system.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 31, 1993
- Accession Number
- ADA274163
Entities
People
- John K. Chapin
Organizations
- Hahnemann University Hospital