Relationship Between Changes in Serum Thyrotropin and Total and Lipoprotein Cholesterol with Prolonged Antarctic Residence

Abstract

Antarctic residence (AR) is associated with a 50% increase in the thyrotropin (TSH) response to TSH-releasing hormone (TRH) and an expended triiodothyronine (T3) distribution volume and extravascular hormone pool, collectively called the polar T3 syndrome. To investigate the possible biologic significance of this syndrome, we studied the relationship between nonstimulated TSH and serum lipid profiles in nine subjects, once while in California and monthly during 9 months of AR. We measured serum levels of TSH, total thyroxine (TT4), free T4(FT4), total T3(TT3), free T3(FT3), thyroid-binding globulin (TBG) , total cholesterol (T-CHOL), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), dietary cholesterol (D-CHOL), dietary fat (D-FAT), and dietary kilocalories at each month.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1993
Accession Number
ADA274262

Entities

People

  • H. L. Reed
  • I. E. Sapien
  • M. T. Morris
  • R. R. Harford
  • R. Warden

Organizations

  • Naval Medical Research Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood Coagulation
  • Body Weight
  • Carrier Proteins
  • Chemistry
  • Cholesterol
  • Digestive System Processes
  • Endocrine Glands
  • High Density
  • Hormones
  • Kinetics
  • Lipids
  • Medical Personnel
  • Pituitary And Hypothalamic Hormones And Analogues
  • Regression Analysis
  • Statistical Analysis
  • Thyroid Hormones

Fields of Study

  • Medicine

Readers

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  • Geochemistry
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