The Influence of Multiple Host Contacts on the Acquisition and Transmission of Dengue-2 Virus
Abstract
I tested assumptions of the hypothesis that multiple host contacts by Ae. aegypti contribute to dengue virus transmission, the hypothesis assumes multiple meals that combine a viremic meal with a meal from an immune host will not interfere with mosquito infection. I administered enemas, which simulated a second meal from an immune host, to Ae. aegypti that had fed 24 hours earlier from a drop of dengue-2 virus infected blood. Infection rates of the mosquitoes receiving immune sera (85%) were significantly lower than the controls (92%). Lower infection rates reduce the potential for virus transmission. In vitro transmission rates of the mosquitoes that become infected were not altered by the immune sera.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1993
- Accession Number
- ADA275299
Entities
People
- John L. Putnam
Organizations
- Air Force Institute of Technology