Effects of Pressure on Membrane-Associated Receptors and Effector Elements

Abstract

To identify the effects of moderate hydrostatic pressure on receptor and effector elements involved in transmembrane signal transduction, we examined the A1 adenosine receptor - inhibitory G protein (G) - adenylylcyclase signal transduction complex. Our experiments were designed to identify and define at the molecular level pressure effects on system components in isolation and on the entire functional complex.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 30, 1993
Accession Number
ADA275813

Entities

People

  • Joseph F. Siebenaller

Organizations

  • Louisiana State University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Adenosine
  • Barometric Pressure
  • Brain
  • Cell Physiological Processes
  • Couplings
  • Deep Oceans
  • Fish
  • Hydrostatic Pressure
  • Membranes
  • Nucleotides
  • Protein Sequence Analysis
  • Proteins

Readers

  • Breast cancer cell signaling and growth regulation.
  • Electrical Engineering
  • Molecular and Cellular Biochemistry