The Effect of Cementation and Autogenous Bone Grafting on Allograft Union and Incorporation
Abstract
The phase I in vitro testing of intact control bones and experimental bones where the segmental allograft is held in place by an interlocking nail with or without the addition of medullary cement is currently underway utilizing a protocol similar to that described above. The testing should be completed by May 31, 1994, in Phase II of this study, an in vivo dog model will be used to perform segmental replacement of the mid-diaphysis (6-cm) of the femur with an immunologically mismatched allograft stabilized with an interlocking nail with and without cementation of the medullary canal. Additionally, the effect of the addition of autogenous bone graft (periosteally, endosteally, or both periosteally) on healing, mineral content, bone remodeling, and limb function will be assessed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 09, 1994
- Accession Number
- ADA276464
Entities
People
- Mark D. Markel
Organizations
- University of Wisconsin Madison School of Veterinary Medicine